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KMID : 0861120140180010067
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Korean Journal of Oriental Preventive Medicine
2014 Volume.18 No. 1 p.67 ~ p.82
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Analysis of Clinical Researches on Traditional Medicine Treatment for Behcet’s Disease in Korea, China, and Japan.
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Yong Seok-il
Gu Hyun-Gyung
Kim Dae-Hun
Son Kyung-Woo
Yun Young-Ju
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Abstract
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Objective : To find a treatment strategy, this study aimed to review and compare the clinical studies ofKorea, China, and Japan on traditional medicine treatment for Behcet’s disease.
Method : Literature searches were performed on six databases in each country and English databases,such as OASIS, KoreanTK, CNKI, J-STAGE, PubMed, and Cochrane CENTRAL. In addition, using the limitedkeywords, the area was restricted to traditional medicine treatment, but the period was not limited. Studieswere categorized according to the study design and we analyzed the difference of treatment among threecountries.
Results : One hundred and forty-one clinical studies met our inclusion criteria: 11 studies in Korea, 15 inJapan, 115 in China. Randomized controlled trials (RCT) have increased in China, however, no RCT wasreported in Korea and Japan. The method of treatment was mainly traditional herbal medicine in all thethree countries, but there were significant differences in the field of syndrome identification and prescriptionamong countries. The studies in China made use of most various treatment modalities and reportedthe highest effectiveness.
Conclusion : Traditional medicine treatment showed a considerable effect for improving various symptomsof Behcet’s disease. However, more research for answering the safety and well-designed studies consideringcharacteristics of Behcet’s disease should be performed to evaluate the effectiveness of traditional medicinetreatment objectively in the future.
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KEYWORD
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Behcet’s disease, Traditional Korean medicine, Traditional Chinese medicine, Kampo medicine, Clinical Study
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